Born in Berlin in 1989, Lisa Hrdina was a member of the youth theatre group P14 at the Volksbühne am Rosa-Luxemburg-Platz from 2007 to 2010. There, in 2009, she acted in Du hast mir die Pfanne versaut, du Spiegelei des Terrors (You Ruined my Pan, you Fried Egg of Terror) and Ein Chor irrt sich gewaltig (A Choir is Totally Wrong) by René Pollesch. From 2010 to 2014 she studied acting at the University of the Arts Berlin. During her studies, she appeared in productions at the Maxim Gorki Theater, the Hans Otto Theater in Potsdam, the Deutsches Theater Berlin and the Sophiensäle. Since 2014 she has been a member of the Deutsches Theater ensemble. She has collaborated with Daniela Löffner, Thorsten Lensing, Claudia Bauer, Tom Kühnel, Jürgen Kuttner, Anne Lenk, Tilmann Köhler, Friederike Heller, Dušan David Pařízek and Stephan Kimmig. She also works in radio, film and TV. 2019, Lisa Hrdina was rewarded with the Mario-Adorf-Prize for her outstanding performance.